1,3-Thiazolbenzamide Derivatives as Chikungunya Virus nsP2 Protease Inhibitors
Larisa Ivanova, Kai Rausalu, Eva Žusinaite, Jaana Tammiku‐Taul, Andres Merits, Mati Karelson
Abstract
with CHIKV nsP2 showed that a possible mechanism of action of these compounds is the blocking of the active site and the catalytic dyad of nsP2.
Topics & Concepts
ChikungunyaAlphavirusVirologyVirusSindbis virusBiologyViral replicationAlphavirus infectionDocking (animal)RNAMedicineBiochemistryNursingGeneMosquito-borne diseases and controlHIV Research and TreatmentViral Infections and Outbreaks Research