Membrane active Janus-oligomers of β<sup>3</sup>-peptides
Imola Cs. Szigyártó, Judith Mihály, András Wacha, Dóra Bogdán, Tünde Juhász, Gergely Kohut, Gitta Schlosser, Ferenc Zsila, Vlada B. Urlacher, Zoltán Varga, Ferenc Fülöp, Attila Bóta, István M. Mándity, Tamás Beke‐Somfai
Abstract
lipid transfer proteins. For the tested, peptides the mixed chirality pattern resulted in similar assemblies despite sequential differences. Based on this, it is hoped that the presented molecular framework will inspire similar oligomers with diverse functionality.
Topics & Concepts
ChemistryHydrogen bondMembraneLipid bilayerMolecular dynamicsSupramolecular chemistryIntermolecular forcePeptideMoleculeSide chainChirality (physics)BilayerStereochemistryCombinatorial chemistryOrganic chemistryPolymerBiochemistryComputational chemistryNambu–Jona-Lasinio modelChiral symmetry breakingQuantum mechanicsQuarkPhysicsChemical Synthesis and AnalysisSupramolecular Self-Assembly in MaterialsRNA and protein synthesis mechanisms