The lipid peroxidation product 4-hydroxynonenal inhibits NLRP3 inflammasome activation and macrophage pyroptosis
Chia George Hsu, Camila Lage Chávez, Chongyang Zhang, Mark P. Sowden, Yan Chen, Bradford C. Berk
Topics & Concepts
InflammasomePyroptosis4-HydroxynonenalChemistryCell biologyCaspase 1Lipid peroxidationEndogenyAIM2InflammationOxidative stressImmunologyBiochemistryBiologyInflammasome and immune disordersHeme Oxygenase-1 and Carbon MonoxideGout, Hyperuricemia, Uric Acid