Litcius/Paper detail

SARS-CoV-2 Seroprevalence among a Southern U.S. Population Indicates Limited Asymptomatic Spread under Physical Distancing Measures

Amir Barzin, John L. Schmitz, Samuel P. Rosin, Rameet Sirpal, Martha Almond, Carole Robinette, Samantha Wells, Michael G. Hudgens, Andrew F. Olshan, Stephanie Deen, Patrick Krejci, Eugenia Quackenbush, Kevin Chronowski, Caleb Cornaby, Janette L. Goins, LINDA K. BUTLER, Julia Aucoin, Kim L. Boyer, Janet Faulk, Devena E. Alston-Johnson, Cristen P. Page, Yijun Zhou, Lynne C. Fiscus, Blossom Damania, Dirk P. Dittmer, David B. Peden

2020mBio29 citationsDOIOpen Access PDF

Abstract

This study suggests limited but accelerating asymptomatic spread of SARS-CoV-2. Asymptomatic infections, like symptomatic infections, disproportionately affected vulnerable communities in this population, and seroprevalence was higher in African American participants than in White participants. The low, overall prevalence may reflect the success of shelter-in-place mandates at the time this study was performed and of maintaining effective physical distancing practices among suburban populations. Under these public health measures and aggressive case finding, outbreak clusters did not spread into the general population.

Topics & Concepts

AsymptomaticSeroprevalenceMedicineCohortPopulationCohort studyPandemicPediatricsDemographyCoronavirus disease 2019 (COVID-19)Internal medicineEnvironmental healthImmunologySerologyDiseaseAntibodyInfectious disease (medical specialty)SociologySARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research StudiesSARS-CoV-2 detection and testing