Amelioration of post-traumatic osteoarthritis via nanoparticle depots delivering small interfering RNA to damaged cartilage
Sean K. Bedingfield, Juan M. Colazo, Fang Yu, Danielle D. Liu, Meredith A. Jackson, Lauren E. Himmel, Hongsik Cho, Leslie J. Crofford, Karen A. Hasty, Craig L. Duvall
Topics & Concepts
OsteoarthritisCartilageSmall interfering RNAMatrix metalloproteinaseExtracellular matrixInflammationAggrecanType II collagenMedicineRNACancer researchChemistryPharmacologyCell biologyPathologyImmunologyInternal medicineAnatomyBiologyBiochemistryArticular cartilageGeneAlternative medicineOsteoarthritis Treatment and MechanismsKnee injuries and reconstruction techniquesCell Adhesion Molecules Research