NLRP12-PANoptosome activates PANoptosis and pathology in response to heme and PAMPs
Balamurugan Sundaram, Pandian Nagakannan, Raghvendra Mall, Yaqiu Wang, Roman Sarkar, Hee Jin Kim, R. K. Subbarao Malireddi, Rajendra Karki, Laura J. Janke, Peter Vogel, Thirumala‐Devi Kanneganti
Topics & Concepts
InflammasomeInflammationBiologyInnate immune systemCaspase 1Programmed cell deathCell biologyPyroptosisAIM2ImmunologyHemeApoptosisImmune systemBiochemistryEnzymeInflammasome and immune disordersHeme Oxygenase-1 and Carbon Monoxideinterferon and immune responses