Pleckstrin-2 promotes tumour immune escape from NK cells by activating the MT1-MMP-MICA signalling axis in gastric cancer
Deli Mao, Zhijun Zhou, Hengxing Chen, Xinran Liu, Dongsheng Li, Xiancong Chen, Yulong He, Mingyang Liu, Changhua Zhang
Topics & Concepts
Cancer researchImmune systemBiologyPI3K/AKT/mTOR pathwayProtein kinase BFlow cytometryCancer cellNatural killer cellCell culturePleckstrin homology domainMolecular biologyCytotoxic T cellCancerImmunologyIn vitroSignal transductionCell biologyGeneticsBiochemistryImmune Cell Function and InteractionReproductive System and PregnancyImmune cells in cancer