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Proposal of a Taxonomic Nomenclature for the Bacillus cereus Group Which Reconciles Genomic Definitions of Bacterial Species with Clinical and Industrial Phenotypes

Laura M. Carroll, Martin Wiedmann, Jasna Kovač

2020mBio204 citationsDOIOpen Access PDF

Abstract

Historical species definitions for many prokaryotes, including pathogens, have relied on phenotypic characteristics that are inconsistent with genome evolution. This scenario forces microbiologists and clinicians to face a tradeoff between taxonomic rigor and clinical interpretability. Using the Bacillus cereus group as a model, a conceptual framework for the taxonomic delineation of prokaryotes which reconciles genomic definitions of species with clinically and industrially relevant phenotypes is presented. The nomenclatural framework outlined here serves as a model for genomics-based bacterial taxonomy that moves beyond arbitrarily set genomospecies thresholds while maintaining congruence with phenotypes and historically important species names.

Topics & Concepts

NomenclatureBacillus cereusPhenotypeCereusBiologyComputational biologyEvolutionary biologyTaxonomic rankMicrobiologyGeneticsTaxonomy (biology)ZoologyBacteriaEcologyGeneTaxonBacillus and Francisella bacterial researchProbiotics and Fermented FoodsBacteriophages and microbial interactions
Proposal of a Taxonomic Nomenclature for the Bacillus cereus Group Which Reconciles Genomic Definitions of Bacterial Species with Clinical and Industrial Phenotypes | Litcius