Fluorescence lifetime microscopy unveils the supramolecular organization of liposomal Doxorubicin
Paolo Maria Tentori, Giovanni Signore, Andrea Camposeo, Annalisa Carretta, Gianmarco Ferri, Pasqualantonio Pingue, Stefano Luin, Daniela Pozzi, Enrico Gratton, Fabio Beltram, Giulio Caracciolo, Francesco Cardarelli
Abstract
is present on both liposome-membrane leaflets. We argue that the present experimental protocol can be applied to the investigation of the supramolecular organization of encapsulated luminescent drugs/molecules all the way from the production phase to their state within living matter.
Topics & Concepts
PhasorLiposomeSupramolecular chemistryFluorescenceMembraneFluorescence-lifetime imaging microscopyFluorescence microscopeBiophysicsChemistryMaterials scienceNanotechnologyMoleculeOrganic chemistryBiologyOpticsPhysicsBiochemistryElectric power systemQuantum mechanicsPower (physics)Nanoparticle-Based Drug DeliveryNanoplatforms for cancer theranosticsLuminescence and Fluorescent Materials