Tectorigenin enhances PDX1 expression and protects pancreatic β-cells by activating ERK and reducing ER stress
Xinlei Yao, Kun Li, Liang Chen, Zilong Zhou, Jiao Wang, Shuyue Wang, Lei Liu, Chunlei Yu, Zhenbo Song, Yongli Bao, Lihua Zheng, Ying Sun, Guannan Wang, Yanxin Huang, Jingwen Yi, Luguo Sun, Yuxin Li
Abstract
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Topics & Concepts
PDX1MAPK/ERK pathwayUnfolded protein responseCell biologyChemistryCancer researchMedicineBiologyKinaseBiochemistryTranscription factorEndoplasmic reticulumGenePancreatic function and diabetesAdenosine and Purinergic SignalingEndoplasmic Reticulum Stress and Disease