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Excited-state palladium-catalysed reductive alkylation of imines: scope and mechanism

Rajesh Kancherla, Krishnamoorthy Muralirajan, Magnus Rueping

2022Chemical Science46 citationsDOIOpen Access PDF

Abstract

Palladium catalysis induced by visible-light irradiation is a promising tool for promoting unusual chemical reactivity. Here, the hybrid alkyl radical/Pd( i ) species generated is used to promote the reductive alkylation of imines.

Topics & Concepts

AlkylChemistryPalladiumAlkylationExcited stateCatalysisPhotochemistryReductive eliminationReaction mechanismCombinatorial chemistryOrganic chemistryPhysicsNuclear physicsCatalytic C–H Functionalization MethodsRadical Photochemical ReactionsSynthesis and Catalytic Reactions
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