Neutrophil-like pH-responsive pro-efferocytic nanoparticles improve neurological recovery by promoting erythrophagocytosis after intracerebral hemorrhage
Linfeng Fan, Lulu Jin, Tianchi Tang, Yonghe Zheng, Zihang Chen, Haopu Lin, Chao Ding, Tingting Wang, Huaijun Chen, Yinghan Guo, Chaoran Xu, Hang Zhou, Xinyan Wu, Xiongjie Fu, Feng Yan, Zhengwei Mao, Gao Chen
Abstract
This biomimetic nanomedicine is envisaged to offer an encouraging strategy to effectively promote hematoma and inflammation resolution, consequently alleviate ICH progression.
Topics & Concepts
Intracerebral hemorrhageInflammationMedicineBlood–brain barrierChemistryNeurosciencePharmacologyImmunologyCentral nervous systemAnesthesiaInternal medicineBiologySubarachnoid hemorrhagePhagocytosis and Immune RegulationIntracerebral and Subarachnoid Hemorrhage ResearchImmune cells in cancer