Insulinomas: from diagnosis to treatment. A review of the literature.
Dimitrios Giannis, Dimitrios Moris, Georgia Sofia Karachaliou, Diamantis I. Tsilimigras, Georgios Karaolanis, Alexandros Papalampros, Evangelos Felekouras
2021PubMed60 citations
Abstract
Insulinoma is the most common pancreatic neuroendocrine tumor (NET). Insulinomas are most commonly benign, well-differentiated NETs, whereas malignant neoplasms account for approximately 5-10% of all cases. Management includes conservative treatment with drugs targeting insulin-induced hypoglycemia, non-operative invasive procedures, as well as curative open or laparoscopic tumor resection. The current review aimed to summarize the current literature evidence on insulinoma and investigate the advantages and complications of available treatments.
Topics & Concepts
InsulinomaMedicineHypoglycemiaNeuroendocrine tumorsInsulinResectionGeneral surgeryIntensive care medicineInternal medicineSurgeryNeuroendocrine Tumor Research AdvancesNeuroblastoma Research and Treatments