Litcius/Paper detail

Enlarging the substrate binding pocket of penicillin G acylase from Achromobacter sp. for highly efficient biosynthesis of β-lactam antibiotics

Zhen Yan, Bin Huang, Kai Yang, Richmond Anaman, Charles Amanze, Jing Jin, Hongbo Zhou, Guanzhou Qiu, Weimin Zeng

2023Bioorganic Chemistry10 citationsDOI

Topics & Concepts

ChemistryHydrolysisCombinatorial chemistryPenicillinStereochemistryBarbituric acidLactamMutantBiocatalysisSubstrate (aquarium)BiochemistryAntibioticsCatalysisGeneIonic liquidGeologyOceanographyEnzyme Catalysis and ImmobilizationEnzyme Production and CharacterizationSteroid Chemistry and Biochemistry