Protective action of pomegranate peel polyphenols in type 2 diabetic rats<i>via</i>the translocation of Nrf2 and FoxO1 regulated by the PI3K/Akt pathway
Weimin Zhang, Chen Hou, Lin Du, Xitong Zhang, Mi Yang, Li Chen, Jianke Li
Abstract
. Pomegranate extracts may show great potential and application prospects as functional foods or preventive drugs to improve pancreatic beta cell dysfunction and provide a reference for future development in health care.
Topics & Concepts
FOXO1Protein kinase BPI3K/AKT/mTOR pathwayPhosphorylationIn vivoChemistryInsulinChromosomal translocationPharmacologyInternal medicineSignal transductionCell biologyEndocrinologyBiochemistryBiologyMedicineBiotechnologyGenePomegranate: compositions and health benefitsHops Chemistry and ApplicationsCynara cardunculus studies