Litcius/Paper detail

Design, synthesis, and evaluation of novel 3-thiophene derivatives as potent fungistatic and fungicidal reagents based on a conformational restriction strategy

Wenbo Yin, Lei Liu, Hong Jiang, Tianxiao Wu, Hengxian Cui, Yuxin Zhang, Zixuan Gao, Yin Sun, Qiaohua Qin, Liyu Zhao, Xin Su, Dongmei Zhao, Maosheng Cheng

2022European Journal of Medicinal Chemistry14 citationsDOIOpen Access PDF

Topics & Concepts

ChemistryAzoleFungicideThiopheneLead compoundDrugAntifungal drugReagentCombinatorial chemistryDrug resistanceAntifungalEchinocandinsPharmacologyMicrobiologyAmphotericin BBiochemistryIn vitroOrganic chemistryBiologyCaspofunginBotanyAntifungal resistance and susceptibilitySynthesis and Biological EvaluationSynthesis and biological activity