Design, synthesis, and evaluation of a novel benzamidine-based inhibitor of VEGF-C binding to Neuropilin-2
Ahmed M. Said, Matthew W. Parker, Craig W. Vander Kooi
Topics & Concepts
BenzamidineChemistryNeuropilin 1Drug discoverySmall moleculeInternalizationLigand (biochemistry)BiophysicsReceptorCancer researchBiochemistryVEGF receptorsEnzymeVascular endothelial growth factorBiologyAngiogenesis and VEGF in CancerLymphatic System and DiseasesAxon Guidance and Neuronal Signaling