Probiotic <i>Bacillus</i> Affects Enterococcus faecalis Antibiotic Resistance Transfer by Interfering with Pheromone Signaling Cascades
Yu-Chieh Lin, Eric H.-L. Chen, Rita P.‐Y. Chen, Gary M. Dunny, Wei‐Shou Hu, Kung‐Ta Lee
Abstract
cleaved peptide pheromones without affecting the growth of E. faecalis, thereby reducing the frequency of conjugative plasmid transfer. In addition, a specific cleaved pheromone fragment interfered with conjugative plasmid transfer. These findings provide a potential probiotic-based method for interfering with the transfer of antibiotic resistance between E. faecalis strains.
Topics & Concepts
Enterococcus faecalisMicrobiologyProbioticAntibioticsAntibiotic resistanceEnterococcusBiologyBacteriaBacillus subtilisBacillus (shape)Staphylococcus aureusGeneticsProbiotics and Fermented FoodsClostridium difficile and Clostridium perfringens researchGut microbiota and health