Treatment of Nontuberculous Mycobacterial (NTM) Pulmonary Infection in the US Bronchiectasis and NTM Registry: Treatment Patterns, Adverse Events, and Adherence to American Thoracic Society/Infectious Disease Society of America Treatment Guidelines
Jennifer H Ku, Emily Henkle, Timothy R. Aksamit, Alan R. Barker, Amanda E. Brunton, Kevin Winthrop
Abstract
Among 1038 participants with pulmonary Mycobacterium avium complex and 120 with Mycobacterium abscessus enrolled in the US Bronchiectasis and NTM Research Registry, less than half received antibiotic therapy in the 24 months before registry enrollment, of which less than half were guideline based. Adverse effects occurred in 21% of therapy recipients, of whom 33% discontinued therapy.
Topics & Concepts
MedicineBronchiectasisNontuberculous mycobacteriaMycobacterium avium complexGuidelineMycobacterium abscessusAdverse effectIntensive care medicineInternal medicineInfectious disease (medical specialty)DiseaseAntibioticsMycobacteriumPathologyTuberculosisLungMicrobiologyBiologyMycobacterium research and diagnosisInfectious Diseases and MycologyTuberculosis Research and Epidemiology