Litcius/Paper detail

Chitosan‐ZnO: An Efficient and Recyclable Polymer Incorporated Hybrid Nanocatalyst to Synthesize Tetrahydrobenzo[ <i>b</i> ]pyrans and Pyrano[2,3‐ <i>d</i> ]pyrimidinones under Microwave Expedition

Aravind R. Nesaragi, Tilak Gasti, Tukaram V. Metre, Ashish Anand, Ravindra R. Kamble, Ravindra B. Chougale, Rangappa S. Keri

2022ChemistrySelect18 citationsDOI

Abstract

Abstract The innovation of facile, efficient and mild procedures utilizing contemptible, conveniently separable and reusablesolid catalysts that overcome obstacles are invariably in demand. Hence, a straightforward one‐pot multicomponent reaction (MCR) and an expedient procedure for the synthesis of pyran annulated heterocycles 5 a – k and 6 l – v is developed using Chitosan‐Zinc oxide (CS‐ZnO) hybrid nanocatalyst. Use of aqueous medium is one of the major highlight of the present protocol. This protocol renders ease of operation, facile work up and magnified yields (90–95 %) as well as explores the use of modified polymeric substrates in the organic synthesis.

Topics & Concepts

ChitosanPyranPyrimidinonesMichael reactionCombinatorial chemistryPolymerCatalysisMicrowaveMaterials scienceChemistryNanotechnologyOrganic chemistryChemical engineeringComputer scienceTelecommunicationsEngineeringMulticomponent Synthesis of HeterocyclesSynthesis and biological activitySynthesis of heterocyclic compounds