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Plasma proteome analyses in individuals of European and African ancestry identify cis-pQTLs and models for proteome-wide association studies

Jingning Zhang, Diptavo Dutta, Anna Köttgen, Adrienne Tin, Pascal Schlosser, Morgan E. Grams, Benjamin Harvey, Bing Yu, Eric Boerwinkle, Josef Coresh, Nilanjan Chatterjee

2022Nature Genetics383 citationsDOIOpen Access PDF

Topics & Concepts

ProteomeBiologyQuantitative trait locusGenetic associationGeneticsExpression quantitative trait lociGenome-wide association studyGenetic admixturePhenotypeProteomicsComputational biologyPopulationBioinformaticsGenotypeSingle-nucleotide polymorphismGeneDemographySociologyGout, Hyperuricemia, Uric AcidAlcohol Consumption and Health EffectsGenetic Associations and Epidemiology