Advancing equity in human genomics through tissue-specific multi-ancestry molecular data
Ana Luiza Arruda, Andrew P. Morris, Eleftheria Zeggini
Abstract
There is a pressing need to generate molecular data from diverse tissues across global populations. These currently missing data are necessary to resolve genome-wide association study loci, identify effector genes, and move the translational genomics needle beyond European-ancestry individuals and the minority of diseases for which blood is the relevant tissue.
Topics & Concepts
GenomicsBiologyComputational biologyHuman genomeGenome-wide association studyComparative genomicsGenomePersonal genomicsGeneticsGeneEvolutionary biologyData scienceGenotypeComputer scienceSingle-nucleotide polymorphismGenetic Associations and EpidemiologyMolecular Biology Techniques and ApplicationsCancer Genomics and Diagnostics