Comprehensive Recommendations for the Clinical Management of Pregnant Women With Noninvasive Prenatal Test Results Suspicious of a Maternal Malignancy
Catharina J. Heesterbeek, Liesbeth Lenaerts, Vivianne C. G. Tjan‐Heijnen, Frédéric Amant, Maartje C. van Rij, Miel Theunis, Christine de Die‐Smulders, Joris Vermeesch, Merryn Macville
Abstract
In this article, we defined comprehensive recommendations for the clinical follow-up of pregnant women with a malignancy-suspicious NIPT result, on the basis of the vast experience with population-based NIPT screening programs in two European countries complemented with published large data sets. These recommendations provide a tool for classifying NIPT results as malignancy-suspicious, and guide health care professionals in structured clinical decision making for the diagnostic process of pregnant women who receive such a malignancy-suspicious NIPT result.
Topics & Concepts
MalignancyMedicineTest (biology)ObstetricsHealth professionalsGynecologyPopulationHealth careFamily medicinePathologyPaleontologyEnvironmental healthEconomic growthEconomicsBiologyPrenatal Screening and DiagnosticsCancer Risks and FactorsRenal and related cancers