Litcius/Paper detail

Branched pegylated linker-auristatin to control hydrophobicity for the production of homogeneous minibody-drug conjugate against HER2-positive breast cancer

Emmanuel Douez, Émilie Allard-Vannier, Imène Ait Mohamed Amar, Louis Jolivet, Fanny Boursin, Aurélie Maisonial‐Besset, Tiffany Witkowski, Jean‐Michel Chezal, Cyril Colas, Stéphanie Letast, Etienne Auvert, Caroline Denevault‐Sabourin, Nicolas Aubrey, Nicolas Joubert

2024Journal of Controlled Release22 citationsDOI

Topics & Concepts

Antibody-drug conjugateConjugateIn vivoEx vivoPharmacologyLinkerBiodistributionInternalizationMedicineTrastuzumabImmunoconjugateCytotoxicityDrugBreast cancerCancer researchChemistryCancerIn vitroAntibodyMonoclonal antibodyImmunologyInternal medicineReceptorBiochemistryBiologyOperating systemComputer scienceMathematicsBiotechnologyMathematical analysisHER2/EGFR in Cancer ResearchMonoclonal and Polyclonal Antibodies ResearchCAR-T cell therapy research
Branched pegylated linker-auristatin to control hydrophobicity for the production of homogeneous minibody-drug conjugate against HER2-positive breast cancer | Litcius