Chili pepper extends lifespan in a concentration-dependent manner and confers cold resistance on <i>Drosophila melanogaster</i> cohorts by influencing specific metabolic pathways
Uliana Semaniuk, Dmytro V. Gospodaryov, Olha Strilbytska, Alicja Z. Kucharska, Anna Sokół‐Łętowska, Nadia Burdyliuk, Kenneth B. Storey, Maria M. Bayliak, Oleh Lushchak
Abstract
, death in early ages). The metabolic changes caused by consumption of chili-supplemented food had a pronounced dependence on gender. A characteristic of both fruit fly sexes that ate chili-supplemented food was an increased resistance to cold shock. Flies of both sexes had lower levels of hemolymph glucose when they ate food supplemented with low concentrations of chili powder, as compared with controls. However, males fed on food with 3% chili had lower levels of storage lipids and pyruvate reducing activity of lactate dehydrogenase compared with controls. Females fed on this food showed lower activities of hexokinase and pyruvate kinase, as well as lower ADP/O ratios, compared with control flies.