Transcriptomic profiling of murine GnRH neurons reveals developmental trajectories linked to human reproduction and infertility
Yassine Zouaghi, Daniel Alpern, Vincent Gardeux, Julie Russeil, Bart Deplancke, Federico Santoni, Nelly Pitteloud, Andrea Messina
Abstract
We charted the landscape of gene expression dynamics underlying murine GnRH neuron embryonic development. Our study highlights new genes in GnRH neuron development and provides novel insights linking those genes with human reproduction.
Topics & Concepts
TranscriptomeInfertilityBiologyProfiling (computer programming)ReproductionHuman reproductionGene expression profilingNeuroscienceCell biologyComputational biologyBioinformaticsAndrologyGeneMedicineGene expressionGeneticsPregnancyComputer scienceOperating systemEpigenetics and DNA MethylationCongenital heart defects researchGenomics and Chromatin Dynamics