Mechanism of NAIP—NLRC4 inflammasome activation revealed by cryo-EM structure of unliganded NAIP5
Bhaskar Paidimuddala, Jianhao Cao, Grady Nash, Qing Xie, Hao Wu, Liman Zhang
Topics & Concepts
NLRC4InflammasomeCell biologyBiologyChemistryBiochemistryReceptorCaspase 1Inflammasome and immune disordersEndoplasmic Reticulum Stress and DiseaseHeme Oxygenase-1 and Carbon Monoxide