Halogen-Bonding-Enabled Photoinduced Atom Transfer Radical Addition/Cyclization Reaction Leading to Tricyclic Heterocycles
Eiji Yamaguchi, Masanobu Murai, Akichika Itoh
Abstract
Atom transfer radical addition (ATRA) reactions are crucial for the dual functionalization of unsaturated hydrocarbons. Radical generation, pivotal in ATRA, has seen advancements from thermal to photochemical methods. Recent focus on halogen-bonding-based radical generation, including our group's innovative photochemical approach, offers cost-effective alternatives to transition-metal-dependent photocatalysts. This eliminates the need for high-energy UV light, enhancing the efficiency with noncovalent interactions.
Topics & Concepts
ChemistryPhotochemistryHalogenAtom (system on chip)Surface modificationHalogen bondRing (chemistry)Combinatorial chemistryOrganic chemistryEmbedded systemAlkylPhysical chemistryComputer scienceRadical Photochemical ReactionsOxidative Organic Chemistry ReactionsSulfur-Based Synthesis Techniques