Grpel2 alleviates myocardial ischemia/reperfusion injury by inhibiting MCU-mediated mitochondrial calcium overload
Rongjin Yang, Xiaomeng Zhang, Pingping Xing, Shun Zhang, Feiyu Zhang, Jianbang Wang, Jun Yu, Xiaoling Zhu, Pan Chang
Topics & Concepts
Gene knockdownMitochondrial fissionMitochondrionReperfusion injuryOxidative stressIschemiaApoptosisCell biologyUniporterMedicineDownregulation and upregulationCalciumChemistryCytosolPharmacologyBiologyCardiologyInternal medicineBiochemistryGeneEnzymeMitochondrial Function and PathologyEndoplasmic Reticulum Stress and DiseaseCardiovascular Function and Risk Factors