Design, synthesis and biological evaluation of 2-aminopyridine derivatives as USP7 inhibitors
Xiaoming Xu, Mingchen Wang, Hailong Xu, Na Liu, Kaixian Chen, Cheng Luo, Shijie Chen, Hua Chen
Topics & Concepts
ChemistrySurface plasmon resonanceInhibitory postsynaptic potentialIC50Lead compoundCombinatorial chemistryStereochemistryWestern blotIn vitroBiochemistryGeneNanotechnologyMaterials scienceBiologyNanoparticleNeuroscienceUbiquitin and proteasome pathwaysCancer-related Molecular PathwaysGenetics and Neurodevelopmental Disorders