Loganin and catalpol exert cooperative ameliorating effects on podocyte apoptosis upon diabetic nephropathy by targeting AGEs-RAGE signaling
Yuping Chen, Jing Chen, Ming Jiang, Yingxue Fu, Yihui Zhu, Ni Jiao, Liping Liu, Qiu Du, Hongyan Wu, Huiqin Xu, Jihu Sun
Topics & Concepts
PodocyteRage (emotion)Diabetic nephropathyCatalpolPharmacologyMAPK/ERK pathwayApoptosisp38 mitogen-activated protein kinasesGlycationInternal medicineMedicineChemistryEndocrinologyCancer researchSignal transductionBiologyDiabetes mellitusCell biologyKidneyBiochemistryPathologyProteinuriaNeuroscienceAlternative medicineRenal Diseases and GlomerulopathiesChronic Kidney Disease and DiabetesChemotherapy-induced organ toxicity mitigation