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Lipoic acid-induced oxidative stress abrogates IGF-1R maturation by inhibiting the CREB/furin axis in breast cancer cell lines

Diana Farhat, Sandra E. Ghayad, Philippe Icard, Muriel Le Romancer, Nader Hussein, Hubert Lincet

2020Oncogene19 citationsDOI

Topics & Concepts

FurinBiologyCancer researchCREBCell growthProprotein convertaseDownregulation and upregulationCarcinogenesisCancer cellCancerEstrogen receptorTranscription factorCell biologyBreast cancerEndocrinologyBiochemistryLDL receptorEnzymeGeneticsLipoproteinCholesterolGeneBiochemical Acid Research StudiesCancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer
Lipoic acid-induced oxidative stress abrogates IGF-1R maturation by inhibiting the CREB/furin axis in breast cancer cell lines | Litcius