Combination of Mycological Criteria: a Better Surrogate to Identify COVID-19-Associated Pulmonary Aspergillosis Patients and Evaluate Prognosis?
Sarah Dellière, Emmanuel Dudoignon, Sébastian Voicu, Magalie Collet, Sofiane Fodil, Benoit Plaud, Benjamin Chousterman, Stéphane Bretagne, Elie Azoulay, Alexandre Mebazaa, François Dépret, Bruno Mégarbane, Alexandre Alanio
Abstract
Diagnosis of coronavirus disease 2019 (COVID-19)-associated pulmonary aspergillosis (CAPA) remains unclear especially in nonimmunocompromised patients. The aim of this study was to evaluate seven mycological criteria and their combination in a large homogenous cohort of patients.
Topics & Concepts
GalactomannanMedicineInternal medicineBronchoalveolar lavageAspergillosisAspergillusGastroenterologyCohortRespiratory systemImmunologyRespiratory diseaseCohort studyBlood cultureMortality rateMechanical ventilationCOPDPathologyMycosisCause of deathSputumRisk factorRespiratory failureRetrospective cohort studyPredictive value of testsPneumoniaAntifungal resistance and susceptibilityInfective Endocarditis Diagnosis and ManagementInterstitial Lung Diseases and Idiopathic Pulmonary Fibrosis