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First Patient-to-Patient Intrahospital Transmission of Clade I Candida auris in France Revealed after a Two-Month Incubation Period

Alexandre Alanio, Hannah Marie Snell, Camille Cordier, Marie Desnos‐Ollivier, Sarah Dellière, Nesrine Aissaoui, Aude Sturny-Leclère, Élodie Da Silva, Cyril Eblé, M. Rouveau, Micheline Thégat, Widad Zebiche, Matthieu Lafaurie, Blandine Denis, Sophie Touratier, Mourad Benyamina, Emmanuel Dudoignon, Samia Hamane, Christina A. Cuomo, François Dépret

2022Microbiology Spectrum26 citationsDOIOpen Access PDF

Abstract

While large outbreaks of C. auris in hospital settings have been described, few clear cases of direct transmission have been documented. We here investigated the transmission of C. auris clade I between two patients with a 41- to 61-day delay between exposure and the development of colonization. This may lead to changes in the recommendations concerning treatment of C. auris cases, as an incubation period of this length is one of the first to be reported.

Topics & Concepts

Candida aurisIncubation periodTransmission (telecommunications)CladeMedicineOutbreakIncubationBiologyVirologyAntifungalDermatologyPhylogenetic treeEngineeringGeneElectrical engineeringBiochemistryAntifungal resistance and susceptibilityFungal Infections and StudiesPneumocystis jirovecii pneumonia detection and treatment
First Patient-to-Patient Intrahospital Transmission of Clade I Candida auris in France Revealed after a Two-Month Incubation Period | Litcius