Synthesis of new thiourea derivatives and metal complexes: Thermal behavior, biological evaluation, in silico ADMET profiling and molecular docking studies
Tuncay Yeşilkaynak, Fatma Nur Özkömeç, Mustafa Çeşme, Ruken Esra Demirdöğen, Emine Kutlu, Hatice Mehtap Kutlu, Fatih Mehmet Emen
Topics & Concepts
ChemistryIn silicoDocking (animal)ThioureaIn vitroStereochemistryIC50MTT assayMetalProton NMRMolecular modelCombinatorial chemistryBiochemistryOrganic chemistryGeneNursingMedicineSynthesis and biological activityMetal complexes synthesis and propertiesSynthesis and Characterization of Heterocyclic Compounds