Exploring the therapeutic potential and bioactive compounds in Pyrus species
Sonia Singh, Riya Verma, Himanshu Sharma
Abstract
• Pyrus species are rich in bioactive compounds such as flavonoids, polyphenols, terpenoids, and vitamins. • The major phytochemicals in pears include quercetin, catechins, chlorogenic acid, and anthocyanins, which contribute to their antioxidant properties. • It has several pharmacological activities such as anti-oxidant, antidiabetic, anti-inflammatory and miscellaneous properties. The genus Pyrus encompasses a diverse range of species the Chinese pear ( Pyrus ussuriensis; Pyrus bretschneideri ), Japanese pear ( Pyrus pyrifolia ), and the European pear ( Pyrus communis ) that have been extensively studied for their phytochemical constituents and associated pharmacological activities. This manuscript provides significant data regarding the phytochemistry and pharmacological impact of many species of Pyrus . The data was gathered from electronic repositories that included Science Direct, Web of Science, Scopus, and PubMed. This review aims to provide a comprehensive overview of the bioactive compounds present in Pyrus species and their potential therapeutic applications. The phytoconstituents identified in Pyrus plants include a variety of phenolic compounds, flavonoids, triterpenoids, and organic acids. These phytochemicals contribute to the diverse pharmacological properties exhibited by Pyrus species, such as anti-inflammatory, antimicrobial, antioxidant, antibacterial, hepatoprotective and anticancer activities.