A double-blind placebo-controlled randomized phase II trial assessing the activity and safety of regorafenib in non-adipocytic sarcoma patients previously treated with both chemotherapy and pazopanib
Nicolas Penel, Olivier Mir, Jennifer Wallet, Isabelle Ray‐Coquard, Axel Le Cesne, Antoîne Italiano, Sébastien Salas, Corinne Delcambre, Emmanuelle Bompas, François Bertucci, Esma Saâda-Bouzid, L. Chaigneau, Christine Chevreau, Thomas Brodowicz, Emilie Decoupigny, Marie Vanseymortier, Lucie Laroche, S. Taïeb, Marie‐Cécile Le Deley, Jean‐Yves Blay
Topics & Concepts
RegorafenibMedicinePazopanibHazard ratioPlaceboInternal medicineClinical endpointAdverse effectSoft tissue sarcomaProgression-free survivalSurgeryRandomized controlled trialChemotherapyConfidence intervalGastroenterologyOncologyCancerPathologyColorectal cancerSoft tissueAlternative medicineSunitinibSarcoma Diagnosis and TreatmentManagement of metastatic bone diseaseLung Cancer Treatments and Mutations