Differential GLP-1R Binding and Activation by Peptide and Non-peptide Agonists
Xin Zhang, Matthew J. Belousoff, Peishen Zhao, Albert J. Kooistra, Tin T. Truong, Sheng Yu Ang, Christina Rye Underwood, Thomas Egebjerg, Petr Šenel, Gregory D. Stewart, Yi-Lynn Liang, Alisa Glukhova, Hariprasad Venugopal, Arthur Christopoulos, Sebastian G. B. Furness, Laurence J. Miller, Steffen Reedtz‐Runge, Christopher J. Langmead, David E. Gloriam, Radostin Danev, Patrick M. Sexton, Denise Wootten
Topics & Concepts
PeptideBiologyG protein-coupled receptorReceptorAgonistRational designGlucagon-like peptide 1 receptorBiochemistryCell biologyComputational biologyPharmacologyGeneticsReceptor Mechanisms and SignalingNeuropeptides and Animal PhysiologyDiabetes Treatment and Management