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Organelle synergy unleashed: Modulating mitochondrial-endoplasmic reticulum contacts with a self-assembled prodrug amplifies ferroptosis for innovative cancer therapy

Junyan Zhuang, Renming Fan, Weike Liao, Ruizhuo Lin, Aohua Deng, Ting Zhao, Yongrui Hai, Heran Li, Lei Tang, Gaofei Wei

2024Chemical Engineering Journal18 citationsDOI

Topics & Concepts

Endoplasmic reticulumProdrugOrganelleMitochondrionCell biologyCancerCancer therapyChemistryPharmacologyMedicineBiologyBiochemistryInternal medicineFerroptosis and cancer prognosisRNA modifications and cancerATP Synthase and ATPases Research
Organelle synergy unleashed: Modulating mitochondrial-endoplasmic reticulum contacts with a self-assembled prodrug amplifies ferroptosis for innovative cancer therapy | Litcius