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Direct inhibition of Keap1-Nrf2 Protein-Protein interaction as a potential therapeutic strategy for Alzheimer's disease

Yi Sun, Jiaxuan Huang, Yufei Chen, Hao Shang, Wannian Zhang, Jian‐Qiang Yu, Ling He, Chengguo Xing, Chunlin Zhuang

2020Bioorganic Chemistry64 citationsDOIOpen Access PDF

Topics & Concepts

KEAP1NeuroprotectionChemistryOxidative stressWestern blotPharmacologySuperoxide dismutaseGlutathioneHippocampusBiochemistryEndocrinologyBiologyEnzymeTranscription factorGeneGenomics, phytochemicals, and oxidative stressFamily Support in IllnessAluminum toxicity and tolerance in plants and animals
Direct inhibition of Keap1-Nrf2 Protein-Protein interaction as a potential therapeutic strategy for Alzheimer's disease | Litcius