Gpbar-1/cAMP/PKA signaling mitigates macrophage-mediated acute cholestatic liver injury via antagonizing NLRP3-ASC inflammasome

Lin Zhuang, Naixin Jia, Li Zhang, Qi Zhang, Samuel O. Antwi, Kurt Sartorius, Kejia Wu, Donglin Sun, Dong Xi, Yunjie Lu

2024Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease11 citationsDOI

Topics & Concepts

Gene knockdownInflammasomeLiver injuryInflammationBile acidLipopolysaccharideSignal transductionApoptosisChemistryImmunologyCancer researchMedicineInternal medicineBiologyCell biologyBiochemistryDrug Transport and Resistance MechanismsLiver Diseases and ImmunityInflammasome and immune disorders