Using nickel to fold discrete synthetic macromolecules into single-chain nanoparticles
Melissa A. Reith, Sinan Kardas, Chiel Mertens, Mathieu Fossepré, Mathieu Surin, Jan Steinkoenig, Filip Du Prez
Abstract
Sequence-defined macromolecules were prepared with a thiolactone-based platform whereby ligand functionalities were introduced along the backbone enabling a nickel induced formation of single-chain nanoparticles.
Topics & Concepts
MacromoleculeFold (higher-order function)NanoparticleNickelSequence (biology)Single chainChain (unit)ChemistryCombinatorial chemistryNanotechnologyMaterials scienceComputer scienceOrganic chemistryBiochemistryPhysicsBiologyAntibodyAstronomyProgramming languageImmunologySupramolecular Self-Assembly in MaterialsDendrimers and Hyperbranched PolymersNanomaterials for catalytic reactions