LIGHT/TNFSF14 promotes CAR-T cell trafficking and cytotoxicity through reversing immunosuppressive tumor microenvironment
Na Zhang, Xiaohong Liu, Juliang Qin, Yue Sun, Hao Xiong, Boxu Lin, Kexin Liu, Binghe Tan, Chenglin Zhang, Chenshen Huang, Shancheng Ren, Mingyao Liu, Bing Du
Topics & Concepts
Immune systemTumor microenvironmentCancer researchCytotoxicityCytokineTumor necrosis factor alphaBiologyCytotoxic T cellCCL19ImmunologyChemokineIn vitroBiochemistryChemokine receptorCAR-T cell therapy researchImmune Cell Function and InteractionT-cell and B-cell Immunology