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m1A and m6A modifications function cooperatively to facilitate rapid mRNA degradation

Sung Ho Boo, Hongseok Ha, Yoon Ki Kim

2022Cell Reports59 citationsDOIOpen Access PDF

Abstract

A-facilitated rapid degradation. Together, our observations provide compelling evidence for crosstalk between different RNA modifications.

Topics & Concepts

RNAMessenger RNARNase PRNA-binding proteinCell biologyBiologyCrosstalkP-bodiesNonsense-mediated decayTranscriptomeGene expressionGeneGeneticsRNA splicingTranslation (biology)OpticsPhysicsRNA modifications and cancerRNA Research and SplicingCancer-related molecular mechanisms research
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