Perspectives of mitochondria-lysosome-related organelle in hepatocyte dedifferentiation and implications in chronic liver disease
Xiaowen Ma, Hong‐Min Ni, Wen‐Xing Ding
Abstract
According to the widely accepted ‘endosymbiotic theory’, mitochondria are originated from bacteria when the eukaryotic cell evolved from the capture of alphaproteobacteria, within primitive archaea around 2 billion years ago, which set a symbiotic relationship between the captured bacterium
Topics & Concepts
ArchaeaOrganelleMitochondrionAlphaproteobacteriaEndosymbiosisCell biologyBiologyLysosomeEukaryotic cellBacteriaHepatocyteCellAutophagyEvolutionary biologyGeneticsBiochemistryPlastidGeneApoptosisIn vitroChloroplast16S ribosomal RNAEnzymeMitochondrial Function and PathologyLiver Disease Diagnosis and TreatmentMetabolism and Genetic Disorders