Cryo-EM structure of an amyloid fibril formed by full-length human prion protein
Liqiang Wang, Kun Zhao, Han‐Ye Yuan, Qiang Wang, Zeyuan Guan, Jing Tao, Xiangning Li, Yunpeng Sun, Chuan-Wei Yi, Jie Chen, Dan Li, Delin Zhang, Ping Yin, Cong Liu, Yi Liang
Topics & Concepts
FibrilChemistryBiophysicsIn vitroAmyloid (mycology)Protein foldingRecombinant DNAProtein structurePrion proteinHelix (gastropod)Protein aggregationBiochemistryBiologyDiseaseEcologyInorganic chemistryMedicineGenePathologySnailPrion Diseases and Protein MisfoldingTrace Elements in HealthNeurological diseases and metabolism