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Antiproliferative effect of bacterial cyclodipeptides in the HeLa line of human cervical cancer reveals multiple protein kinase targeting, including mTORC1/C2 complex inhibition in a TSC1/2-dependent manner

Laura Hernández-Padilla, Homero Reyes de la Cruz, Jesús Campos‐García

2020APOPTOSIS15 citationsDOI

Topics & Concepts

PI3K/AKT/mTOR pathwayProtein kinase BCancer researchmTORC1MAPK/ERK pathwayKinaseWnt signaling pathwayBiologyRPTORSignal transductionHeLamTORC2ChemosensitizerP70-S6 Kinase 1ChemistryCell biologyCell cultureCytotoxicityBiochemistryGeneticsIn vitroCancer Mechanisms and TherapyPeptidase Inhibition and AnalysisCancer Research and Treatments
Antiproliferative effect of bacterial cyclodipeptides in the HeLa line of human cervical cancer reveals multiple protein kinase targeting, including mTORC1/C2 complex inhibition in a TSC1/2-dependent manner | Litcius