Data-driven discovery of near-infrared type I photosensitizers for RNA-targeted tumor photodynamic therapy
Wen Chen, Xinjie Mao, Xiaozhi Wang, Ya-Cong Liao, Xiao-Yue Yin, Hai‐Long Wu, Tai-Yi Chen, Meng-Qing Liu, Tong Wang, Ru‐Qin Yu
Abstract
PDT experiments. It showed satisfactory phototoxicity and significant tumor inhibition. Our approach establishes an intelligent discovery paradigm to accelerate the identification of NIR type I PSs for advanced PDT.
Topics & Concepts
Photodynamic therapyCancer researchRNAPhotosensitizerComputational biologyChemistryMedicineBiologyPhotochemistryBiochemistryOrganic chemistryGeneNanoplatforms for cancer theranosticsPhotodynamic Therapy Research Studies