Thiophene-linked tetramethylbodipy-labeled nucleotide for viscosity-sensitive oligonucleotide probes of hybridization and protein–DNA interactions
Pedro Güixens‐Gallardo, Jana Humpolíčková, Sebastian Paul Miclea, Radek Pohl, Tomáš Kraus, Piotr Jurkiewicz, Martin Hof, Michal Hocek
Abstract
TP was transported to live cells where its interactions could be detected by FLIM but it did not show incorporation to genomic DNA in cellulo.
Topics & Concepts
ChemistryOligonucleotideNucleotideDNAThiopheneNucleic acid thermodynamicsDNA–DNA hybridizationMolecular biologyBiochemistryBase sequenceGeneOrganic chemistryBiologyAdvanced biosensing and bioanalysis techniquesDNA and Nucleic Acid ChemistryLuminescence and Fluorescent Materials