Iodine(III)-catalyzed benzylic oxidation by using the (PhIO)<sub>n</sub>/Al(NO<sub>3</sub>)<sub>3</sub> system
Berencie Yahuaca-Juárez, Gerardo González, Marco Antonio Ramírez‐Morales, Calara Alba-Betancourt, Martha Alicia Devezé-Álvarez, Claudia Leticia Mendoza-Macías, Rafael Ortíz‐Alvarado, Kevin A. Juárez‐Ornelas, César R. Solorio‐Alvarado, Keiji Maruoka
Abstract
The first iodine(III)-based procedure for the benzylic oxidation of different arenes is described by using the (PhIO)n/Al(NO3)3 system under catalytic conditions leading to the formation of the corresponding carbonyl derivatives. The method proceeds under mild, operationally simple, room temperature, short reaction times, and open flask conditions. In light of the organocatalysis relevance and the novelty of our protocol, we wish to communicate our initial results of this novel oxidation.
Topics & Concepts
ChemistryCatalysisIodineNoveltyOrganocatalysisRedoxSimple (philosophy)Combinatorial chemistryOrganic chemistryPhilosophyEpistemologyEnantioselective synthesisTheologyOxidative Organic Chemistry ReactionsVanadium and Halogenation ChemistryChemical Synthesis and Reactions